Adlard, P.A., Perreau, V.M., Pop, V., & Cotman, C.W. (2005). Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer’s disease. Journal of Neuroscience, 25, 4217-4221.
Brenner, I.K., Natale, V.M., Vasilious, P., Moldoveanu, A.I., Shek, P.N., & Shepherd, R.J. (2009). Impact of three different types of exercise on components of inflammatory response. European Journal Applied Physiology, 80, 452-60.
Espinosa-Aguirre, J., & Abdullaev, F. (2004). Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials. Cancer Detection and Prevention, 28(6), 426-432.
Farinha, J. B., Steckling, F. M., Stefanello, S. T., Cardoso, M. S., Nunes, L. S., Barcelos, R. P., ... & Soares, F. A. A. (2015). Response of oxidative stress and inflammatory biomarkers to a 12-week aerobic exercise training in women with metabolic syndrome. Sports Medicine-Open, 1(1), 1-10.
Foroghan, M., Jafari, Z., Shirinbayan, P., Ghaemmagham Farahani, Z., & Rahgozar, M. (2008). Validation of mini- mental state examination (MMSE) in The elderly population of tehran. Advanced Cognitive Science Journal, 10(2),29‐37. [In Persian]
Ghadami, M.R., & Pourmotabbed, A. (2009). The effect of Crocin on scopolamine induced spatial learning and memory deficits in rats. Iranian Journal Physiology and Pharmacology, 173(1), 112-115. [In Persian]
Gholami, M., Dehghankar, L., & Ghazalian, F. (2020). Effects of 8 weeks combined training along with Zataria Multiflora supplement ingestion on serum levels of MCP-1 and insulin resistance in verweight men. Journal of Practical Studies of Biosciences in Sport, 8(16), 34-46. [In Persian]
Greig, N.H., Mattson, M.P., Perry, T., Chan, S.L., Giordani, T., Sambamurti, K., … & Lahiri, D.K. (2004). New therapeutic strategies and drug candidates for neurodegenerative diseases: p53 and TNF-α inhibitors, and GLP-1 receptor agonists. Annals of the New York Academy of Sciences, 1035(1), 290-315.
Ha, I. (2009). Mild cognitive impairment (MCI): Pathogenesis and treatments. Clinical Psychopharmacology and Neuroscience, 7(1), 3-8.
Hematfar, A., Shahsavari, A., & Mousavi, S.R. (2012). The effect of eight weeks of selected aerobic exercise on the depression and serum serotonin concentration in depressed female university students. Journal of Sport Biosciences, 13, 51-62. [In Persian]
Hooshmand-Moghadam, B., Eskandari,M., Shabkhiz, F., Mojtahedi, S., & Mahmoudi, N. (2021). Saffron (Crocus sativus L.) in combination with resistance training reduced blood pressure in the elderly hypertensive men. British Journal of Clinical Pharmacology, 87(8), 3255-3267.
Hosseinzadeh, H., Sadegnia, H.R., Motamedshariaty, V., Ghaeni, F.A., & Mohajeri, S.A. (2012). Effects of saffron (Crocus sativus L.) and its active constituent, crocin, on recognition and spatial memory after chronic cerebral hypoperfusion in rats. Phytotherapy Research, 26(3), 381-386. [In Persian]
Isanejad, A., Saraf, Z. H., Mahdavi, M., Gharakhanlou, R., Shamsi, M. M., & Paulsen, G. (2015). The effect of endurance training and downhill running on the expression of IL-1β, IL-6, and TNF-α and HSP72 in rat skeletal muscle. Cytokine, 73(2), 302-308.
Jiang, H., Hampel, H., Prvulovic, D., Wallin, A., Blennow, K., Li, R., & Shen, Y. (2011). Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease. Molecular Neurodegeneration, 6(1), 1-8.
Kamalipour, M., & Akhondzadeh, S. (2011). Cardiovascular effects of Saffron: An vidence-based review. Journal of Tehran University Heart Center, 6(2), 59-61. [In Persian]
Karamian, R., Mohammadian, A., Hassanimoghadam, E., Alizadeh, L., Abdali, N., Keshvari, M., … & Beyranvand, K. (2015). Identification and comparison of the yield and composition of essential oil constituents of four Eucalyptus species adapted to the climatic conditions of Khorramabad. Journal Hermed Pharmacology, 4(1), 25-28. [In Persian]
Khalili, M., & Hamzeh, F. (2010). Effects of active constituents of Crocus sativus L. Crocin on Streptozocin-induced model of Sporadic Alzheimer’s disease in male rats. Iranian Biomedical Journal, 14(1), 59-65. [In Persian]
Knudsen, S.H., & Pedersen, B.K. (2015). Targeting inflammation through a physical active lifestyle and pharmaceuticals for the treatment of type 2 diabetes. Current Diabet Reports,15(10), 82.
Kohanpour, M.A., Peeri, M., & Azarbayjani, M.A. (2017). The effects of aerobic exercise with lavender essence use on cognitive state and serum brain-derived neurotrophic factor levels in elderly with mild cognitive impairment. Journal Herbmed Pharmacology, 6(2), 80-84. [In Persian]
Meeusen, R., & De Meirleir, K. (2005). Exercise and brain neurotransmission. Sports Medicine, 20(3), 160-88.
Melnyk, J.P., Wang, S., & Marcone, M.F. (2010). Chemical and biological properties of the world’s most expensive spice: Saffron. Food Research International, 43(8), 1981-1989.
Miller, D. I., Taler, V., Davidson, P. S., & Messier, C. (2012). Measuring the impact of exercise on cognitive aging: methodological issues. Neurobiology of Aging, 33(3), 622-e29.
Modaresi, M., & Messripour, M., Marghmaleki, M. (2009). Effect of saffron extract on electrophoretic pattern of serum proteins in the male mice. Scientific Journal Kurdistan University of Medical Sciences, 13(4), 23-9. [In Persian]
Nillson, J., Parker, M.G., & Kabir, Z.N. (2004). Assessing health–relatel quality of life among older people in Rural Bangladesh. Journal of Trans Cultural Nursing, 15(4), 298-307.
Papandreou, M.A., Tsachaki, M., Efthimiopoulos, S., Cordopatis, P., Lamari, F. N., & Margarity, M. (2011). Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection. Behavioural Brain Research, 219(2), 197-204.
Pitsikas, N. & Sakellaridis, N., (2006). Crocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the rat. Behavioural Brain Research, 173(1), 112-115.
Sadeghlu, R. (2009). Population and development in Iran: Dimensions and challenges Tehran.National Population Studies & Comprehensive Management Institute, 2(3), 43-53. [In Persian]
Samarghandian, S., Azimi- Nezhad, M., & Farkhondeh, T. (2016). Crocin attenuate tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) in streptozotocin-induced diabetic rat aorta. Cytokine, 88, 20-28. [In Persian]
Shati, A., Elsaid, F., & Hafez, E. (2011). Biochemical and molecular aspects of aluminium chloride-induced neurotoxicity in mice and the protective role of Crocus sativus L. extraction and honey syrup. Neuroscience, 175(23), 66-74.
Speaker, K.J., Cox, S.S., Paton, M.M., Serebrakian, A., Maslanik, T., Greenwood, B.N., & Fleshner, M. (2014). Six weeks of voluntary wheel running modulates inflammatory protein (MCP-1, IL-6, and IL-10) and DAMP (Hsp72) responses to acutestress in white adipose tissue of lean rats. Brain, Behavior, and Immunity, 39, 87-98.
Swardfager, W., Lanctôt, K., Rothenburg L,. Wong, A., Cappell, J., & Herrmann, N. (2010). A meta-analysis of cytokines in Alzheimer’s disease. Biological Psychiatry, 68, 930-941.
Tolouei azar, G., Saberi,Y., Tofighi, A. & Ghorbanian, B. (2020). Effects of 10 weeks of continuous aerobic training and Sesamin supplementation on serum levels of Interleukin-6 and Interleukin-1 Beta in trained men. Journal of Practical Studies of Biosciences in Sport, 8(16), 8-19. [In Persian]
Zafer, S., Aldhehri, W., & AL-Bishri, H. (2017). Saffron (Crocus Sativus) ameliorates Tnbc-induced colitis in rats via downregulation of inflammatory cytokines TNF-α and IL- 10, caspases-3 gene expression and oxidative stress in experimental rats. Pharmaceutical Sciences, 7, 1-9.
